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Bioanalytics

Our divsion of bioanalytics combines our expertise in biochemistry, molecular biology, as well as cell- and immune-biology. We offer, besides standard techniques, a specialized platform for testing biomolecules and their biological effects.

Nucleic Acid Analytics

  • Identity and purity testing of nucleic acids by standard electrophoretic, PCR-based, spectroscopic and/or staining techniques
  • Copy number determination of your target by Real-Time PCR

Protein/Peptide Analytics

  • Protein purity and identity testing by electrophoretic techniques (Ph. Eur. 2.2.31, Ph. Eur. 2.2.54) and Western-Blot
  • Protein Identity by AA COMPOSITION (Ninhydrin positive substances, Ph. Eur. 2.2.56)
  • Amino Acid Analysis of raw materials (Ninhydrin positive substances, Ph. Eur. 2.2.56)
  • Determination of protein concentration (Ph. Eur. 2.5.33) and ELISA techniques

Immune- and Cell Analytics

  • Performance of analyte specific stability and proof of unwanted immunogenicity / PK-STUDIES (according to ICH M3, EMEA, FDA)
  • Cytokine profiling (minimal sample amount and multiplexing)
  • Immunoprofiling of PBMCS
  • Enzyme-linked immunosorbent assays (ELISA)
  • Flow Cytometry (Ph. Eur. 2.7.24)

Cell culture based bioassays and potency assays

  • Performance of analyte specific cell effector assays (APOPTOSIS, ADCC, CDC)
  • Proliferation/Reporter gene assays
  • Implementation and performance of analyte specific in-vitro potency assays
  • Assay of Heparin (Ph. Eur. 2.7.5)

MicroMol offers you a diverse platform for the GMP compliant analytics of your biomolecule. From standard techniques to custom made bioassays. We support you on analytical method development, analytical method validation/verification/transfer, and on routine analysis of your test items.

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